The BCCM consortium has joined the Global Genome Biodiversity Network (GGBN) as observer member. The GGBN is a global network of well-managed collections of genomic tissue samples from across the Tree of Life, benefiting society through biodiversity research, development and conservation. The BCCM collections offer their microbial strains also as genomic DNA samples, and want to share their experiences with other colleagues in the genomics field.
Millions of microbial taxa inhabit the rhizosphere and could be used as biofertilizers, biopesticides, and/or for bioremediation. Only a fraction of these microbes have been described and/or are being utilized. Most are dispersed in collections, but coordination of their accessibility and availability is challenging. Here, we present the Pan-European Rhizosphere Resource Network (PERN), which is a transnational repository of microorganisms whose objectives are to facilitate access to rhizosphere resources and information and help users with technical and legal issues.
For applications where a high titer of viable cells is required, such as inocula for bioreactors or supplementation of food or feed matrices, BCCM/LMG offers freeze-drying of bacterial cultures in different volumes (up to 20 ml) in glass vials on request
Since January 2015, the Scientific Institute of Public Health (WIV-ISP) hosting the BCCM/IHEM collection has been certified ISO 14001 for its environmental policy. This certification involves that the institute is committed to a sustainable management of its activities. The latter include waste reduction, energy saving, the compliance with and follow-up of the regulation, the analysis, surveillance and reduction of its environmental impact.
When expressing more than one gene in a cell line, often bicistronic expression vectors with an internal ribosomal entry site (IRES) are used. Instead of these large IRES sequences, a much shorter, self-cleaving 2A peptide (P2A) can be used. The efficient cleaving activity of this peptide was described in Kim et al. (2011; PMID: 21602908).
To make the advantages of the P2A peptide available for all scientists, BCCM/LMBP is proud to announce the bicistronic pEF6-P2A cloning vector.
The 19th congress of the International Society of Human and Animal Mycology (ISHAM) will take place from the 4th until the 8th of May in Melbourne, Australia. BCCM/IHEM is involved in the organization of a workshop on MALDI-TOF MS for the identification of fungi, on the 3th of May. More information can be found here: www.isham2015.com
We are hoping to welcome you in Melbourne!
The hORFv8.1 library consists of a sequence-verified, clonal collection of human Open Reading Frames (ORFs), presented as individual Gateway Entry vectors (backbone: pDONR223).
The new BCCM/LMBP search engine makes the quest for your gene of interest easy, with a database containing, among others, all names and symbols ever assigned to it.
All clones come without a termination codon, allowing the addition of C-terminal tags or markers.
The global burden of multi-drug tuberculosis (MDR-TB) was estimated in 2013 at 5.3% of TB cases, including 9% with extensively drug-resistant tuberculosis (XDR-TB)1. Only 48% of MDR cases were treated successfully, in part due to high toxicity, the long duration of the current regimens, and drug supply interruptions. To overcome these constraints, new TB drugs were deemed essential and have been developed, yet their safety and efficacy are being assessed in Phase II and III clinical trials for patients with MDR-TB.